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Cellosaurus PC-3-Luc2 (CVCL_A4BV)

[Text version]
Cell line name PC-3-Luc2
Accession CVCL_A4BV
Resource Identification Initiative To cite this cell line use: PC-3-Luc2 (RRID:CVCL_A4BV)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-1435-LUC2).
Doubling time: ~16 hours (ATCC=CRL-1435-LUC2).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-1435-LUC2

Markers:
AmelogeninX
CSF1PO11
D5S81813
D7S8208,11
D13S31711
D16S53911
TH016,7
TPOX8,9
vWA17

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Cross-references
Cell line collections (Providers) ATCC; CRL-1435-LUC2
Cell line databases/resources cancercelllines; CVCL_A4BV
Encyclopedic resources Wikidata; Q105510539
Entry history
Entry creation12-Jan-2021
Last entry update10-Sep-2024
Version number8