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Cellosaurus A-431-Luc2 (CVCL_A4BS)

[Text version]
Cell line name A-431-Luc2
Accession CVCL_A4BS
Resource Identification Initiative To cite this cell line use: A-431-Luc2 (RRID:CVCL_A4BS)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-1555-LUC2).
Doubling time: ~22 hours (ATCC=CRL-1555-LUC2).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Sequence variations
  • Gene fusion; HGNC; HGNC:3236; EGFR + HGNC; HGNC:9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-1555-LUC2

Markers:
AmelogeninX
CSF1PO11,12
D5S81812,13
D7S82010
D13S3179,13
D16S53912,14
TH019
TPOX11
vWA15,17

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Cross-references
Cell line collections (Providers) ATCC; CRL-1555-LUC2
Cell line databases/resources cancercelllines; CVCL_A4BS
Encyclopedic resources Wikidata; Q105506024
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number9