ID   AGS-Luc2
AC   CVCL_A4BR
DR   ATCC; CRL-1739-LUC2
DR   cancercelllines; CVCL_A4BR
DR   Wikidata; Q105506382
CC   Population: Caucasian.
CC   Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-1739-LUC2).
CC   Doubling time: ~24 hours (ATCC=CRL-1739-LUC2).
CC   Sequence variation: Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
CC   Transfected with: UniProtKB; P33967; B.cereus Bsr.
CC   Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
ST   Source(s): ATCC=CRL-1739-LUC2
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 12
ST   D16S539: 11,13
ST   D5S818: 9,12
ST   D7S820: 10,11
ST   TH01: 6,7
ST   TPOX: 11,12
ST   vWA: 16,17
DI   NCIt; C4004; Gastric adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0139 ! AGS
SX   Female
AG   54Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 02-05-24; Version: 6
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