ID   BECK-1
AC   CVCL_A4BJ
SY   BECK-1732; Beck-1732
DR   ATCC; CRL-3384
DR   cancercelllines; CVCL_A4BJ
DR   Wikidata; Q105506478
RX   PubMed=30862722;
CC   Karyotypic information: 49~50,XX,+18,+i(21)(q10)x2,+mar[30] (PubMed=30862722).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Unspecified (ATCC=CRL-3384).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Unspecified (ATCC=CRL-3384).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000177778; Zygosity=Unspecified (ATCC=CRL-3384).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): ATCC=CRL-3384
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 12
ST   D16S539: 12
ST   D5S818: 12
ST   D7S820: 12
ST   TH01: 9
ST   TPOX: 11
ST   vWA: 17
DI   NCIt; C8644; B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 19-12-24; Version: 7
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RX   PubMed=30862722; DOI=10.1158/0008-5472.CAN-18-0236; PMCID=PMC6497548;
RA   Diaz-Flores E., Comeaux E.Q., Kim K.L., Melnik E., Beckman K.,
RA   Davis K.L., Wu K., Akutagawa J., Bridges O., Marino R., Wohlfeil M.,
RA   Braun B.S., Mullighan C.G., Loh M.L.-C.;
RT   "Bcl-2 is a therapeutic target for hypodiploid B-lineage acute
RT   lymphoblastic leukemia.";
RL   Cancer Res. 79:2339-2351(2019).
//