ID   SW850
AC   CVCL_A424
SY   SW-850; SW 850
DR   Cosmic; 736278
DR   Cosmic; 933518
DR   GEO; GSM1567856
DR   Wikidata; Q54971214
RX   PubMed=327080;
RX   PubMed=833871;
RX   PubMed=1906154;
RX   PubMed=6220172;
RX   PubMed=8426738;
RX   PubMed=9472115;
RX   PubMed=11787853;
RX   PubMed=25997541;
RX   PubMed=26621286;
CC   Problematic cell line: Possibly misidentified/contaminated. Reported by PubMed=11787853 to contain the same HPV18 sequences as the cervix carcinoma cell line C-4-I (Cellosaurus=CVCL_2253) and to lack mutations in KRAS, TP53, CDKN2A and DPC4 often found in pancreatic adenocarcinoma. Considered by PubMed=25997541 to be a bladder carcinoma cell line.
CC   Part of: UBC-40 urothelial bladder cancer cell line index.
CC   From: Scott and White Clinic; Temple; USA.
CC   Omics: Variations; SNP array analysis.
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 17
//
RX   PubMed=9472115; DOI=10.3892/ijo.12.3.717;
RA   Muller, Carsten
RA   Grosse Bockhorn, Andreas Clemens
RA   Klusmeier, Simone
RA   Kiehl, Michael
RA   Roeder, Christian
RA   Kalthoff, Holger
RA   Koch, Olaf M.
RT   "Lovastatin inhibits proliferation of pancreatic cancer cell lines
RT   with mutant as well as with wild-type K-ras oncogene but has
RT   different effects on protein phosphorylation and induction of
RT   apoptosis.";
RL   Int. J. Oncol. 12:717-723(1998).
//
RX   PubMed=6220172;
RA   Dracopoli, Nicholas C.
RA   Fogh, Jorgen
RT   "Polymorphic enzyme analysis of cultured human tumor cell lines.";
RL   J. Natl. Cancer Inst. 70:469-476(1983).
//
RX   PubMed=11787853; DOI=10.1007/s004280100474;
RA   Moore, Patrick S.
RA   Sipos, Bence
RA   Orlandini, Simonetta
RA   Sorio, Claudio
RA   Real, Francisco X.
RA   Lemoine, Nicholas Robert
RA   Gress, Thomas M.
RA   Bassi, Claudio
RA   Kloppel, Gunter
RA   Kalthoff, Holger
RA   Ungefroren, Hendrik
RA   Lohr, Johannes-Matthias
RA   Scarpa, Aldo
RT   "Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras,
RT   p53, p16 and DPC4/Smad4.";
RL   Virchows Arch. 439:798-802(2001).
//
RX   PubMed=8426738;
RA   Kalthoff, Holger
RA   Schmiegel, Wolff Helmut
RA   Roeder, Christian
RA   Kasche, Daniela
RA   Schmidt, Andreas
RA   Lauer, Georg
RA   Thiele, Heinz-Gunter
RA   Honold, Georg
RA   Pantel, Klaus
RA   Riethmuller, Gert
RA   Scherer, Ewalt
RA   Maurer, Julian
RA   Maacke, Heiko
RA   Deppert, Wolfgang
RT   "p53 and K-RAS alterations in pancreatic epithelial cell lesions.";
RL   Oncogene 8:289-298(1993).
//
RX   PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036;
RA   Earl, Julie
RA   Rico, Daniel
RA   Carrillo-de-Santa-Pau, Enrique
RA   Rodriguez-Santiago, Benjamin
RA   Mendez-Pertuz, Marinela
RA   Auer, Herbert
RA   Gomez, Gonzalo
RA   Grossman, Herbert Barton
RA   Pisano, David G.
RA   Schulz, Wolfgang Arthur
RA   Perez-Jurado, Luis A.
RA   Carrato, Alfredo
RA   Theodorescu, Dan
RA   Chanock, Stephen Jacob
RA   Valencia, Alfonso
RA   Real, Francisco X.
RT   "The UBC-40 Urothelial Bladder Cancer cell line index: a genomic
RT   resource for functional studies.";
RL   BMC Genomics 16:403.1-403.16(2015).
//
RX   PubMed=1906154;
RA   Kalthoff, Holger
RA   Roeder, Christian
RA   Humburg, Inge
RA   Thiele, Heinz-Gunter
RA   Greten, Heiner
RA   Schmiegel, Wolff Helmut
RT   "Modulation of platelet-derived growth factor A- and B-chain/c-sis
RT   mRNA by tumor necrosis factor and other agents in adenocarcinoma
RT   cells.";
RL   Oncogene 6:1015-1021(1991).
//
RX   PubMed=327080; DOI=10.1093/jnci/59.1.221;
RA   Fogh, Jorgen
RA   Fogh, Jens M.
RA   Orfeo, Thomas
RT   "One hundred and twenty-seven cultured human tumor cell lines
RT   producing tumors in nude mice.";
RL   J. Natl. Cancer Inst. 59:221-226(1977).
//
RX   PubMed=833871; DOI=10.1093/jnci/58.2.209;
RA   Fogh, Jorgen
RA   Wright, William C.
RA   Loveless, James D.
RT   "Absence of HeLa cell contamination in 169 cell lines derived from
RT   human tumors.";
RL   J. Natl. Cancer Inst. 58:209-214(1977).
//
RX   PubMed=26621286; DOI=10.1186/s12864-015-2227-4; PMCID=PMC4681452;
RA   Earl, Julie
RA   Rico, Daniel
RA   Carrillo-de-Santa-Pau, Enrique
RA   Rodriguez-Santiago, Benjamin
RA   Mendez-Pertuz, Marinela
RA   Auer, Herbert
RA   Gomez, Gonzalo
RA   Grossman, Herbert Barton
RA   Pisano, David G.
RA   Schulz, Wolfgang Arthur
RA   Perez-Jurado, Luis A.
RA   Carrato, Alfredo
RA   Theodorescu, Dan
RA   Chanock, Stephen Jacob
RA   Valencia, Alfonso
RA   Real, Francisco X.
RT   "Erratum to 'The UBC-40 Urothelial Bladder Cancer cell line index: a
RT   genomic resource for functional studies'.";
RL   BMC Genomics 16:1019.1-1019.2(2015).
//