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Cellosaurus HDC-135 (CVCL_A381)

[Text version]
Cell line name HDC-135
Synonyms HDC135
Accession CVCL_A381
Resource Identification Initiative To cite this cell line use: HDC-135 (RRID:CVCL_A381)
Comments Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Deep proteome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line
STR profile Source(s): PubMed=25926053

Markers:
AmelogeninX
CSF1PO9,11
D5S81810,14
D7S82010,11
D13S3179
D16S53910,12
D21S1126,28
TH019,9.3
TPOX7,8
vWA16,18

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Publications

PubMed=1980607; DOI=10.1002/gcc.2870020112
Bruderlein S., van der Bosch K., Schlag P.M., Schwab M.
Cytogenetics and DNA amplification in colorectal cancers.
Genes Chromosomes Cancer 2:63-70(1990)

PubMed=18258742; DOI=10.1073/pnas.0712176105; PMCID=PMC2268141
Emaduddin M., Bicknell D.C., Bodmer W.F., Feller S.M.
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 105:2358-2362(2008)

PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028
Bracht K., Nicholls A.M., Liu Y., Bodmer W.F.
5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
Br. J. Cancer 103:340-346(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=29101300; DOI=10.15252/msb.20177701; PMCID=PMC5731344
Frejno M., Zenezini Chiozzi R., Wilhelm M., Koch H., Zheng R.-S., Klaeger S., Ruprecht B., Meng C., Kramer K., Jarzab A., Heinzlmeir S., Johnstone E., Domingo E., Kerr D.J., Jesinghaus M., Slotta-Huspenina J., Weichert W., Knapp S., Feller S.M., Kuster B.
Pharmacoproteomic characterisation of human colon and rectal cancer.
Mol. Syst. Biol. 13:951-951(2017)

Cross-references
Encyclopedic resources Wikidata; Q54882146
Gene expression databases GEO; GSM1448069
Polymorphism and mutation databases Cosmic; 715208
Cosmic; 1803943
Proteomic databases PRIDE; PXD005354
PRIDE; PXD005355
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number13