ID   HCE-6
AC   CVCL_A357
DR   BTO; BTO_0005573
DR   cancercelllines; CVCL_A357
DR   Cosmic; 1394514
DR   IARC_TP53; 259
DR   Wikidata; Q54881851
RX   PubMed=2263646;
RX   PubMed=2302677;
RX   PubMed=2415247;
RX   PubMed=2420787;
CC   Doubling time: 27 hours (PubMed=2415247).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Ser (c.832C>T); ClinVar=VCV000376642; Zygosity=Unspecified (PubMed=2263646).
CC   Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
DI   NCIt; C4024; Esophageal squamous cell carcinoma
DI   ORDO; Orphanet_99977; Squamous cell carcinoma of the esophagus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   42Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=2263646; DOI=10.1073/pnas.87.24.9958; PMCID=PMC55293;
RA   Hollstein M.C., Metcalf R.A., Welsh J.A., Montesano R., Harris C.C.;
RT   "Frequent mutation of the p53 gene in human esophageal cancer.";
RL   Proc. Natl. Acad. Sci. U.S.A. 87:9958-9961(1990).
//
RX   PubMed=2302677; DOI=10.1016/0165-4608(90)90073-j;
RA   Whang-Peng J., Banks-Schlegel S.P., Lee E.C.;
RT   "Cytogenetic studies of esophageal carcinoma cell lines.";
RL   Cancer Genet. Cytogenet. 45:101-120(1990).
//
RX   PubMed=2415247;
RA   Banks-Schlegel S.P., Quintero J.;
RT   "Growth and differentiation of human esophageal carcinoma cell
RT   lines.";
RL   Cancer Res. 46:250-258(1986).
//
RX   PubMed=2420787; DOI=10.1016/S0021-9258(17)38506-X;
RA   Banks-Schlegel S.P., Quintero J.;
RT   "Human esophageal carcinoma cells have fewer, but higher affinity
RT   epidermal growth factor receptors.";
RL   J. Biol. Chem. 261:4359-4362(1986).
//