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Cellosaurus HCDB-1 (CVCL_A343)

[Text version]
Cell line name HCDB-1
Synonyms HBP Carcinoma induced by DMBA/BQ extract treatment-1
Accession CVCL_A343
Resource Identification Initiative To cite this cell line use: HCDB-1 (RRID:CVCL_A343)
Comments Characteristics: Buccal pouch carcinoma cell line induced by DMBA and betel quid (BQ).
Doubling time: 19 hours (PubMed=10943946).
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Cheek pouch; UBERON=UBERON_0008802.
Sequence variations
  • Mutation; UniProtKB; Q00366; TP53; Simple; p.Ala141Val (c.422T>C); Zygosity=Unspecified (PubMed=10943946).
Disease Hamster buccal pouch carcinoma (NCIt: C134565)
Species of origin Mesocricetus auratus (Golden hamster) (NCBI Taxonomy: 10036)
Sex of cell Male
Age at sampling 20W
Category Cancer cell line
Publications

PubMed=10943946
Lin S.-C., Chang K.-W., Chang C.-S., Yu S.-Y., Chao S.-Y., Wong Y.-K.
Establishment and characterization of a cell line (HCDB-1) derived from a hamster buccal pouch carcinoma induced by DMBA and Taiwanese betel quid extract.
Proc. Natl. Sci. Counc. Repub. China, B, Life Sci. 24:129-135(2000)

Cross-references
Encyclopedic resources Wikidata; Q54881844
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number13