ID   TSGH-8301
AC   CVCL_A342
SY   TSGH8301; TSGH 8301; Tri-Service General Hospital-8301
DR   BCRC; 60145
DR   cancercelllines; CVCL_A342
DR   Cosmic; 755397
DR   Wikidata; Q54973126
RX   PubMed=3352272;
RX   PubMed=29732388;
CC   Problematic cell line: Contaminated. Shown to be a ME-180 derivative (BCRC and STR profile). Originally thought to originate from a 56 year old male patient with a grade 2 stage A papillary transitional cell carcinoma.
CC   Population: Caucasian.
CC   Doubling time: 26 hours (PubMed=3352272).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68).
CC   Miscellaneous: STR profile from personal communication of Chow N.-H.
CC   Discontinued: BCRC; 60145; true.
CC   Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,13
ST   D16S539: 12,13
ST   D18S51: 12
ST   D19S433: 13,15.2
ST   D21S11: 30,31
ST   D2S1338: 18
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 9,10
ST   D8S1179: 14
ST   FGA: 23
ST   TH01: 8,9.3
ST   TPOX: 8,10
ST   vWA: 15,17
DI   NCIt; C27676; Human papillomavirus-related cervical squamous cell carcinoma
DI   ORDO; Orphanet_213767; Squamous cell carcinoma of the cervix uteri
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1401 ! ME-180
SX   Female
AG   66Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 14
RX   PubMed=3352272; DOI=10.1002/jso.2930370310;
RA   Yeh M.-Y., Yu D.-S., Chen S.-C., Lin M.-S., Chang S.-Y., Ma C.-P.,
RA   Han S.-H.;
RT   "Establishment and characterization of a human urinary bladder
RT   carcinoma cell line (TSGH-8301).";
RL   J. Surg. Oncol. 37:177-184(1988).
RX   PubMed=29732388; DOI=10.3233/BLC-180167;
RA   Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.;
RT   "Systematic review: characteristics and preclinical uses of bladder
RT   cancer cell lines.";
RL   Bladder Cancer 4:169-183(2018).