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Cellosaurus WM1727A (CVCL_A339)

[Text version]
Cell line name WM1727A
Synonyms WM-1727A; WM 1727A
Accession CVCL_A339
Resource Identification Initiative To cite this cell line use: WM1727A (RRID:CVCL_A339)
Comments Part of: Wistar Institute melanoma cell line collection.
Characteristics: Pigmented.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Gene deletion; HGNC; 9588; PTEN; Zygosity=Hemizygous (Wistar).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO10
D2S133820,23
D3S135816,18
D5S81811,12
D7S82011,13
D8S117913,14
D13S31711,12
D16S53912,13
D18S5114
D19S43314
D21S1128,33.2
FGA22
TH019.3
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235
Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R., Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M., Nathanson K.L.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM1727A-01-0001
Cell line databases/resources cancercelllines; CVCL_A339
Encyclopedic resources Wikidata; Q54994193
Gene expression databases GEO; GSM109031
GEO; GSM186473
GEO; GSM186474
Polymorphism and mutation databases Cosmic; 1155559
Cosmic; 1303066
Progenetix; CVCL_A339
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number20