Cellosaurus logo
expasy logo

Cellosaurus WM983C (CVCL_A338)

[Text version]
Cell line name WM983C
Synonyms WM-983C; WM 983C
Accession CVCL_A338
Resource Identification Initiative To cite this cell line use: WM983C (RRID:CVCL_A338)
Comments Part of: Wistar Institute melanoma cell line collection.
Population: Caucasian.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6808 ! WM983A
CVCL_6809 ! WM983B
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX,Y
CSF1PO11
D2S133825,27
D3S135817
D5S81811
D7S82011
D8S11798,13
D13S31712
D16S53911
D18S5114
D19S43310,14
D21S1129,31.2
FGA20,23
TH016
TPOX11
vWA17

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R., Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M., Nathanson K.L.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM983C-01-0001
Cell line databases/resources cancercelllines; CVCL_A338
SKY/M-FISH/CGH; 4949
Encyclopedic resources Wikidata; Q54994348
Gene expression databases GEO; GSM109049
GEO; GSM188069
GEO; GSM188121
GEO; GSM188194
GEO; GSM188209
GEO; GSM188214
GEO; GSM188237
GEO; GSM188267
GEO; GSM188285
GEO; GSM188294
GEO; GSM188326
Polymorphism and mutation databases Cosmic; 1155556
Cosmic; 1187585
Cosmic; 1303083
Progenetix; CVCL_A338
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number23