• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Arg (c.733G>C); ClinVar=VCV000376604; Zygosity=Hemizygous (PubMed=8289498).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220fs (c.658delT); Zygosity=Unspecified (PubMed=20575032).
  

PubMed=8289498
Wada H., Asada M., Nakazawa S., Itoh H., Kobayashi Y., Inoue T., Fukumuro K., Chan L.C., Sugita K., Hanada R., Akuta N., Kobayashi N., Mizutani S.
Clonal expansion of p53 mutant cells in leukemia progression in vitro.
Leukemia 8:53-59(1994)

PubMed=10360377; DOI=10.1038/sj.leu.2401437
Nakamura M., Sugita K., Inukai T., Goi K., Iijima K., Tezuka T., Kojika S., Shiraishi K., Miyamoto N., Karakida N., Kagami K., Koyama-Okazaki T., Mori T., Nakazawa S.
p16/MTS1/INK4A gene is frequently inactivated by hypermethylation in childhood acute lymphoblastic leukemia with 11q23 translocation.
Leukemia 13:884-890(1999)

PubMed=10490826; DOI=10.1038/sj.onc.1202874
Fu X.-Y., McGrath S., Pasillas M., Nakazawa S., Kamps M.P.
EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1.
Oncogene 18:4920-4929(1999)

PubMed=10995006; DOI=10.1038/sj.leu.2401893
Iijima K., Sugita K., Inukai T., Goi K., Tezuka T., Uno K., Sato H., Kagami K., Nakazawa S.
Expression of thrombopoietin receptor and its functional role in human B-precursor leukemia cells with 11q23 translocation or Philadelphia chromosome.
Leukemia 14:1598-1605(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=20575032; DOI=10.1002/ajh.21738; PMCID=PMC7159455
Inukai T., Zhang X.-R., Kameyama T., Suzuki Y., Yoshikawa K., Kuroda I., Nemoto A., Akahane K., Sato H., Goi K., Nakamoto K., Hamada J.-i., Tada M., Moriuchi T., Sugita K.
A specific linkage between the incidence of TP53 mutations and type of chromosomal translocations in B-precursor acute lymphoblastic leukemia cell lines.
Am. J. Hematol. 85:535-537(2010)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)