Publications | PubMed=18035408; DOI=10.1016/j.cell.2007.11.019 Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-872(2007) PubMed=19956543; DOI=10.1371/journal.pone.0008067; PMCID=PMC2780725 Takahashi K., Narita M., Yokura M., Ichisaka T., Yamanaka S. Human induced pluripotent stem cells on autologous feeders. PLoS ONE 4:E8067-E8067(2009) PubMed=21098095; DOI=10.1084/jem.20100844; PMCID=PMC3005234 Takayama N., Nishimura S., Nakamura S., Shimizu T., Ohnishi R., Endo H., Yamaguchi T., Otsu M., Nishimura K., Nakanishi M., Sawaguchi A., Nagai R., Takahashi K., Yamanaka S., Nakauchi H., Eto K. Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J. Exp. Med. 207:2817-2830(2010) PubMed=21460823; DOI=10.1038/nmeth.1591 Okita K., Matsumura Y., Sato Y., Okada A., Morizane A., Okamoto S., Hong H.-J., Nakagawa M., Tanabe K., Tezuka K.-i., Shibata T., Kunisada T., Takahashi M., Takahashi J., Saji H., Yamanaka S. A more efficient method to generate integration-free human iPS cells. Nat. Methods 8:409-412(2011) PubMed=21637780; DOI=10.1371/journal.pgen.1002085; PMCID=PMC3102737 Nishino K., Toyoda M., Yamazaki-Inoue M., Fukawatase Y., Chikazawa E., Sakaguchi H., Akutsu H., Umezawa A. DNA methylation dynamics in human induced pluripotent stem cells over time. PLoS Genet. 7:E1002085-E1002085(2011) PubMed=21900357; DOI=10.1093/hmg/ddr394 Yagi T., Ito D., Okada Y., Akamatsu W., Nihei Y., Yoshizaki T., Yamanaka S., Okano H., Suzuki N. Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum. Mol. Genet. 20:4530-4539(2011) PubMed=22056147; DOI=10.1016/j.scr.2011.10.002 Kunisada Y., Tsubooka-Yamazoe N., Shoji M., Hosoya M. Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells. Stem Cell Res. 8:274-284(2012) PubMed=22802639; DOI=10.1073/pnas.1209979109; PMCID=PMC3411998 Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N., Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S. Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012) PubMed=22848530; DOI=10.1371/journal.pone.0041572; PMCID=PMC3405135 Yagi T., Kosakai A., Ito D., Okada Y., Akamatsu W., Nihei Y., Nabetani A., Ishikawa F., Arai Y., Hirose N., Okano H., Suzuki N. Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research. PLoS ONE 7:E41572-E41572(2012) PubMed=23039195; DOI=10.1186/1756-6606-5-35; PMCID=PMC3546866 Imaizumi Y., Okada Y., Akamatsu W., Koike M., Kuzumaki N., Hayakawa H., Nihira T., Kobayashi T., Ohyama M., Sato S., Takanashi M., Funayama M., Hirayama A., Soga T., Hishiki T., Suematsu M., Yagi T., Ito D., Kosakai A., Hayashi K., Shouji M., Nakanishi A., Suzuki N., Mizuno Y., Mizushima N., Amagai M., Uchiyama Y., Mochizuki H., Hattori N., Okano H. Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol. Brain 5:35.1-35.13(2012) PubMed=23210603; DOI=10.1021/pr300837u Yamana R., Iwasaki M., Wakabayashi M., Nakagawa M., Yamanaka S., Ishihama Y. Rapid and deep profiling of human induced pluripotent stem cell proteome by one-shot NanoLC-MS/MS analysis with meter-scale monolithic silica columns. J. Proteome Res. 12:214-221(2013) PubMed=24259714; DOI=10.1073/pnas.1319061110; PMCID=PMC3870695 Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H., Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N., Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J., Yamanaka S. Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells. Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013) PubMed=24399248; DOI=10.1038/srep03594; PMCID=PMC3884228 Nakagawa M., Taniguchi Y., Senda S., Takizawa N., Ichisaka T., Asano K., Morizane A., Doi D., Takahashi J., Nishizawa M., Yoshida Y., Toyoda T., Osafune K., Sekiguchi K., Yamanaka S. A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells. Sci. Rep. 4:3594-3594(2014) PubMed=24935155; DOI=10.1186/1756-6606-7-45; PMCID=PMC4058693 Yoshida T., Ozawa Y., Suzuki K., Yuki K., Ohyama M., Akamatsu W., Matsuzaki Y., Shimmura S., Mitani K., Tsubota K., Okano H. The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa. Mol. Brain 7:45.1-45.11(2014) PubMed=26626025; DOI=10.1186/s13041-015-0172-4; PMCID=PMC4666063 Shimojo D., Onodera K., Doi-Torii Y., Ishihara Y., Hattori C., Miwa Y., Tanaka S., Okada R., Ohyama M., Shoji M., Nakanishi A., Doyu M., Okano H., Okada Y. Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells. Mol. Brain 8:79.1-79.15(2015) PubMed=27476965; DOI=10.1016/j.stem.2016.06.019 Nishizawa M., Chonabayashi K., Nomura M., Tanaka A., Nakamura M., Inagaki A., Nishikawa M., Takei I., Oishi A., Tanabe K., Ohnuki M., Yokota H., Koyanagi-Aoi M., Okita K., Watanabe A., Takaori-Kondo A., Yamanaka S., Yoshida Y. Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity. Cell Stem Cell 19:341-354(2016) PubMed=27806289; DOI=10.1016/j.celrep.2016.10.026 Ishida Y., Kawakami H., Kitajima H., Nishiyama A., Sasai Y., Inoue H., Muguruma K. Vulnerability of Purkinje cells generated from spinocerebellar ataxia type 6 patient-derived iPSCs. Cell Rep. 17:1482-1490(2016) PubMed=28453617; DOI=10.1093/biolre/iox038 Yokobayashi S., Okita K., Nakagawa M., Nakamura T., Yabuta Y., Yamamoto T., Saitou M. Clonal variation of human induced pluripotent stem cells for induction into the germ cell fate. Biol. Reprod. 96:1154-1166(2017) PubMed=29179815; DOI=10.7554/eLife.21114; PMCID=PMC5705211 Okuno H., Renault-Mihara F., Ohta S., Fukuda K., Kurosawa K., Akamatsu W., Sanosaka T., Kohyama J., Hayashi K., Nakajima K., Takahashi T., Wysocka J.K., Kosaki K., Okano H. CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations. eLife 6:e21114.1-e21114.26(2017) PubMed=28587749; DOI=10.1016/j.jaci.2017.04.013 Takada S., Kambe N., Kawasaki Y., Niwa A., Honda-Ozaki F., Kobayashi K., Osawa M., Nagahashi A., Semi K., Hotta A., Asaka I., Yamada Y., Nishikomori R., Heike T., Matsue H., Nakahata T., Saito M.K. Pluripotent stem cell models of Blau syndrome reveal an IFN-gamma-dependent inflammatory response in macrophages. J. Allergy Clin. Immunol. 141:339-349.e11(2018) PubMed=30127392; DOI=10.1038/s41591-018-0140-5 Fujimori K., Ishikawa M., Otomo A., Atsuta N., Nakamura R., Akiyama T., Hadano S., Aoki M., Saya H., Sobue G., Okano H. Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent. Nat. Med. 24:1579-1589(2018) PubMed=32034090; DOI=10.1074/jbc.RA119.010713; PMCID=PMC7076207 Okubo T., Hayashi R., Shibata S., Kudo Y., Ishikawa Y., Inoue S., Kobayashi Y., Honda A., Honma Y., Kawasaki S., Nishida K. Generation and validation of a PITX2-EGFP reporter line of human induced pluripotent stem cells enables isolation of periocular mesenchymal cells. J. Biol. Chem. 295:3456-3465(2020) PubMed=34287353; DOI=10.3390/mps4030050; PMCID=PMC8293472 Chen C.X.-Q., Abdian N., Maussion G., Thomas R.A., Demirova I., Cai E., Tabatabaei M., Beitel L.K., Karamchandani J., Fon E.A., Durcan T.M. A multistep workflow to evaluate newly generated iPSCs and their ability to generate different cell types. Methods Protoc. 4:50.1-50.21(2021) |