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Cellosaurus MCF-10A CTNNB1 (T41A/+/+) (CVCL_A2PU)

[Text version]
Cell line name MCF-10A CTNNB1 (T41A/+/+)
Synonyms CTNNB1 (T41A/+/+) MCF10A
Accession CVCL_A2PU
Resource Identification Initiative To cite this cell line use: MCF-10A CTNNB1 (T41A/+/+) (RRID:CVCL_A2PU)
Comments Characteristics: Heterozygous knockin of a CTNNB1 activating mutation.
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 2514; CTNNB1; Simple_edited; p.Thr41Ala (c.121A>G); ClinVar=VCV000017580; Zygosity=Heterozygous; Note=By method not specified (Horizon_Discovery=HD+101-009).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
Cell line collections (Providers) Horizon_Discovery; HD+101-009
Encyclopedic resources Wikidata; Q105510074
Entry history
Entry creation12-Jan-2021
Last entry update30-Jan-2024
Version number8