Cellosaurus MDCK-hMDR1 cMDR1-KO (CVCL_A2KA)
| Cell line name | MDCK-hMDR1 cMDR1-KO |
|---|---|
| Synonyms | MDCK-hMDR1cMDR1-KO |
| Accession | CVCL_A2KA |
| Resource Identification Initiative | To cite this cell line use: MDCK-hMDR1 cMDR1-KO (RRID:CVCL_A2KA) |
| Comments | Knockout cell: Method=CRISPR/Cas9; VGNC; 37431; ABCB1. Genetic integration: Method=Transfection; Gene=HGNC; 40; ABCB1. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Omics: Deep quantitative proteome analysis. Derived from site: In situ; Kidney; UBERON=UBERON_0002113. Cell type: Epithelial cell of kidney; CL=CL_0002518. |
| Species of origin | Canis lupus familiaris (Dog) (Canis familiaris)
(NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372. |
| Hierarchy | Parent: CVCL_A2JZ (MDCK2-ABCB1) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=33007277; DOI=10.1016/j.xphs.2020.09.039 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q105510097 |
| Proteomic databases | PRIDE; PXD020238 |
| Entry history | |
| Entry creation | 12-Jan-2021 |
| Last entry update | 10-Sep-2024 |
| Version number | 7 |