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Cellosaurus RD/VCR-F3 (CVCL_A2HQ)

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Cell line name RD/VCR-F3
Accession CVCL_A2HQ
Resource Identification Initiative To cite this cell line use: RD/VCR-F3 (RRID:CVCL_A2HQ)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_28445; Vincristine (VCR).
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1649 (RD)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=7309287; DOI=10.1002/ijc.2910280403
Janet A. Houghton, Peter J. Houghton, Garrett M. Brodeur, Alexander A. Green;
Development of resistance to vincristine in a childhood rhabdomyosarcoma growing in immune-deprived mice.
Int. J. Cancer 28:409-415(1981)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A2HQ
Encyclopedic resources Wikidata; Q105510758
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number8