ID   F3
AC   CVCL_A2GF
DR   PRIDE; PXD019354
DR   Wikidata; Q105506858
RX   PubMed=19914712;
RX   PubMed=20975254;
RX   PubMed=29017582;
RX   PubMed=32942559;
CC   Characteristics: Susceptible to infection by Neospora caninum isolates Nc-Spain7 and Nc-Spain1H (PubMed=29017582).
CC   Doubling time: ~24 hours (Note=In FSM medium) (PubMed=19914712).
CC   Omics: Deep proteome analysis.
CC   Derived from site: In situ; Trophoblast; UBERON=UBERON_0000088.
OX   NCBI_TaxID=9913; ! Bos taurus (Bovine)
SX   Sex unspecified
AG   5FM
CA   Finite cell line
DT   Created: 12-01-21; Last updated: 02-05-24; Version: 6
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RX   PubMed=19914712; DOI=10.1016/j.placenta.2009.10.011;
RA   Hambruch N., Haeger J.-D., Dilly M., Pfarrer C.D.;
RT   "EGF stimulates proliferation in the bovine placental trophoblast cell
RT   line F3 via Ras and MAPK.";
RL   Placenta 31:67-74(2010).
//
RX   PubMed=20975254; DOI=10.1159/000320544;
RA   Haeger J.-D., Hambruch N., Dilly M., Froehlich R., Pfarrer C.D.;
RT   "Formation of bovine placental trophoblast spheroids.";
RL   Cells Tissues Organs 193:274-284(2011).
//
RX   PubMed=29017582; DOI=10.1186/s13071-017-2409-9; PMCID=PMC5634964;
RA   Jimenez-Pelayo L., Garcia-Sanchez M., Regidor-Cerrillo J., Horcajo P.,
RA   Collantes-Fernandez E., Gomez-Bautista M., Hambruch N., Pfarrer C.D.,
RA   Ortega-Mora L.M.;
RT   "Differential susceptibility of bovine caruncular and trophoblast cell
RT   lines to infection with high and low virulence isolates of Neospora
RT   caninum.";
RL   Parasit. Vectors 10:463.1-463.13(2017).
//
RX   PubMed=32942559; DOI=10.3390/pathogens9090749; PMCID=PMC7557738;
RA   Regidor-Cerrillo J., Xia D., Jimenez-Pelayo L., Garcia-Sanchez M.,
RA   Collantes-Fernandez E., Randle N., Wastling J.M., Ortega-Mora L.M.,
RA   Horcajo P.;
RT   "Proteomic characterization of host-pathogen interactions during
RT   bovine trophoblast cell line infection by Neospora caninum.";
RL   Pathogens 9:749.1-749.10(2020).
//