Cellosaurus cell line 91T (CVCL

Cellosaurus 91T (CVCL_A2AT)

Cross-references
Cell line name	91T
Accession	CVCL_A2AT
Resource Identification Initiative	To cite this cell line use: 91T (RRID:CVCL_A2AT)
Comments	From: Siegfried, Jill M.; University of Pittsburgh; Pittsburgh; USA. Miscellaneous: Age of donor from personal communication of Siegfried, Jill M. Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=18645002).
Disease	Lung adenocarcinoma (NCIt: C3512)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Publications	PubMed=10545285; DOI=10.1006/pupt.1999.0210 Siegfried J.M., Krishnamachary N., Gaither Davis A.L., Gubish C.T., Hunt J.D., Shriver S.P. Evidence for autocrine actions of neuromedin B and gastrin-releasing peptide in non-small cell lung cancer. Pulm. Pharmacol. Ther. 12:291-302(1999) PubMed=11929836 Stabile L.P., Davis A.L.G., Gubish C.T., Hopkins T.M., Luketich J.D., Christie N., Finkelstein S., Siegfried J.M. Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen. Cancer Res. 62:2141-2150(2002) PubMed=18645002; DOI=10.1158/1535-7163.MCT-07-2169; PMCID=PMC2556508 Stabile L.P., Rothstein M.E., Keohavong P., Jin J., Yin J.-L., Land S.R., Dacic S., Luong T.M., Kim K.J., Dulak A.M., Siegfried J.M. Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis. Mol. Cancer Ther. 7:1913-1922(2008)
Cell line databases/resources	cancercelllines; CVCL_A2AT
Encyclopedic resources	Wikidata; Q105505987
Entry history
Entry creation	12-Jan-2021
Last entry update	19-Dec-2024
Version number	7