Cellosaurus cell line 343T (CVCL

Cellosaurus 343T (CVCL_A2AK)

Cross-references
Cell line name	343T
Accession	CVCL_A2AK
Resource Identification Initiative	To cite this cell line use: 343T (RRID:CVCL_A2AK)
Comments	From: Siegfried, Jill M.; University of Pittsburgh; Pittsburgh; USA. Miscellaneous: Age/sex of donor and lung cancer type from personal communication of Siegfried, Jill M. Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=18645002).
Disease	Lung adenosquamous carcinoma (NCIt: C9133)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	49Y
Category	Cancer cell line
Publications	PubMed=10545285; DOI=10.1006/pupt.1999.0210 Siegfried J.M., Krishnamachary N., Gaither Davis A.L., Gubish C.T., Hunt J.D., Shriver S.P. Evidence for autocrine actions of neuromedin B and gastrin-releasing peptide in non-small cell lung cancer. Pulm. Pharmacol. Ther. 12:291-302(1999) PubMed=14978140; DOI=10.4049/jimmunol.172.5.3319 Friedman R.S., Bangur C.S., Zasloff E.J., Fan L.-Q., Wang T.-T., Watanabe Y., Kalos M.D. Molecular and immunological evaluation of the transcription factor SOX-4 as a lung tumor vaccine antigen. J. Immunol. 172:3319-3327(2004) PubMed=18645002; DOI=10.1158/1535-7163.MCT-07-2169; PMCID=PMC2556508 Stabile L.P., Rothstein M.E., Keohavong P., Jin J., Yin J.-L., Land S.R., Dacic S., Luong T.M., Kim K.J., Dulak A.M., Siegfried J.M. Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis. Mol. Cancer Ther. 7:1913-1922(2008)
Cell line databases/resources	cancercelllines; CVCL_A2AK
Encyclopedic resources	Wikidata; Q105505909
Entry history
Entry creation	12-Jan-2021
Last entry update	19-Dec-2024
Version number	7