ID   BRE-169
AC   CVCL_A282
SY   BRE169
DR   BTO; BTO:0003754
DR   Wikidata; Q54798211
RX   PubMed=17977821;
CC   Sequence variation: Mutation; HGNC; 43; TAP1; Simple; p.Asp273fs (c.819delC); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C171267; Bare lymphocyte syndrome type 1
DI   ORDO; Orphanet_34592; Immunodeficiency by defective expression of MHC class I
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A5NF ! BRE
SX   Male
AG   16-20Y
CA   Transformed cell line
DT   Created: 06-06-12; Last updated: 10-09-24; Version: 15
//
RX   PubMed=17977821; DOI=10.1074/jbc.M708139200;
RA   Demirel O., Waibler Z., Kalinke U., Grunebach F., Appel S.,
RA   Brossart P., Hasilik A., Tampe R., Abele R.;
RT   "Identification of a lysosomal peptide transport system induced during
RT   dendritic cell development.";
RL   J. Biol. Chem. 282:37836-37843(2007).
//