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Cellosaurus KCL026 (CVCL_A259)

[Text version]
Cell line name KCL026
Synonyms KCL-026; KCL026_SMA
Accession CVCL_A259
Resource Identification Initiative To cite this cell line use: KCL026 (RRID:CVCL_A259)
Comments From: King's College London; London; United Kingdom.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0222.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC11-49.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; HGNC:11117; SMN1; Unexplicit; Ex7-8del; Zygosity=Heterozygous (PubMed=27345977).
Disease Werdnig-Hoffmann disease (NCIt: C98670)
Proximal spinal muscular atrophy type 1 (ORDO: Orphanet_83330)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://www.kcl.ac.uk/lsm/research/divisions/wh/groups/medicine/hescell.aspx
Publications

PubMed=27345977; DOI=10.1016/j.scr.2016.01.005; PMCID=PMC4823667
Hewitson H., Wood V., Kadeva N., Cornwell G., Codognotto S., Stephenson E.L., Ilic D.
Generation of KCL026 research grade human embryonic stem cell line carrying a mutation in SMN1 gene.
Stem Cell Res. 16:249-251(2016)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-13-0222
Encyclopedic resources Wikidata; Q54899672
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number21