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Cellosaurus KCL024 (CVCL_A257)

[Text version]
Cell line name KCL024
Synonyms KCL-024; KCL024_NF1-1
Accession CVCL_A257
Resource Identification Initiative To cite this cell line use: KCL024 (RRID:CVCL_A257)
Comments From: King's College London; London; United Kingdom.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0220.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC11-48.
Donor information: Embryo is sibling to that giving rise to KCL025 (Cellosaurus=CVCL_A258).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT); ClinVar=VCV000420078; Zygosity=Heterozygous (PubMed=27345975).
Disease Neurofibromatosis type 1 (NCIt: C3273)
Neurofibromatosis type 1 (ORDO: Orphanet_636)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Blastocyst stage
Category Embryonic stem cell
Web pages https://www.kcl.ac.uk/lsm/research/divisions/wh/groups/medicine/hescell.aspx
Publications

PubMed=27345975; DOI=10.1016/j.scr.2016.01.010; PMCID=PMC4823759
Hewitson H., Wood V., Kadeva N., Cornwell G., Codognotto S., Stephenson E.L., Ilic D.
Generation of KCL024 research grade human embryonic stem cell line carrying a mutation in NF1 gene.
Stem Cell Res. 16:243-245(2016)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-13-0220
Encyclopedic resources Wikidata; Q54899671
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number24