ID   KCL021
AC   CVCL_A254
SY   KCL-021; KCL021_CF2
DR   NIHhESC; NIHhESC-13-0219
DR   Wikidata; Q38515502
RX   PubMed=27345808;
WW   https://www.kcl.ac.uk/lsm/research/divisions/wh/groups/medicine/hescell.aspx
CC   From: King's College London; London; United Kingdom.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0219.
CC   Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC11-14.
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=27345808).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 25
//
RX   PubMed=27345808; DOI=10.1016/j.scr.2015.12.042; PMCID=PMC4757720;
RA   Miere C., Hewitson H., Wood V., Kadeva N., Cornwell G., Codognotto S.,
RA   Stephenson E.L., Ilic D.;
RT   "Generation of KCL021 research grade human embryonic stem cell line
RT   carrying a deltaF508 mutation in the CFTR gene.";
RL   Stem Cell Res. 16:177-179(2016).
//