Cellosaurus cell line Ma-Mel-79b (CVCL

Cellosaurus Ma-Mel-79b (CVCL_A214)

Cross-references
Cell line name	Ma-Mel-79b
Synonyms	Ma-Mel_79B; Ma-Mel-79B; Ma-Mel 79b; MaMel79b
Accession	CVCL_A214
Resource Identification Initiative	To cite this cell line use: Ma-Mel-79b (RRID:CVCL_A214)
Comments	Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072. Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=16827748; PubMed=17311103).
Disease	Cutaneous nodular melanoma (NCIt: C4225)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_A213 ! Ma-Mel-79
Sex of cell	Male
Age at sampling	41Y
Category	Cancer cell line
Publications	PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R. Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature. Pigment Cell Res. 19:290-302(2006) PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595 Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D. B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis. PLoS ONE 2:E236-E236(2007) PubMed=20544847; DOI=10.1002/gcc.20785 Gast A., Scherer D., Chen B.-W., Bloethner S., Melchert S., Sucker A., Hemminki K., Schadendorf D., Kumar R. Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study. Genes Chromosomes Cancer 49:733-745(2010)
Cell line databases/resources	cancercelllines; CVCL_A214 IGRhCellID; MaMel79b
Encyclopedic resources	Wikidata; Q54903853
Gene expression databases	GEO; GSM109087 GEO; GSM437025
Polymorphism and mutation databases	Cosmic; 1467774 Progenetix; CVCL_A214
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	19