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Cellosaurus Ma-Mel-66b (CVCL_A202)

[Text version]
Cell line name Ma-Mel-66b
Synonyms Ma-Mel_66b; Ma-Mel 66b
Accession CVCL_A202
Resource Identification Initiative To cite this cell line use: Ma-Mel-66b (RRID:CVCL_A202)
Comments Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Cutaneous nodular melanoma (NCIt: C4225)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A201 ! Ma-Mel-66a
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A202
Encyclopedic resources Wikidata; Q54903841
Gene expression databases GEO; GSM109080
Polymorphism and mutation databases Cosmic; 1846661
Cosmic; 2686462
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number14