ID   A549-1
AC   CVCL_A1ZW
DR   cancercelllines; CVCL_A1ZW
DR   Wikidata; Q105506036
RX   PubMed=3032416;
RX   PubMed=3165706;
CC   Population: Caucasian.
CC   Characteristics: Selected to grow at low density.
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 05-10-23; Version: 5
//
RX   PubMed=3032416;
RA   Siegfried J.M.;
RT   "Detection of human lung epithelial cell growth factors produced by a
RT   lung carcinoma cell line: use in culture of primary solid lung
RT   tumors.";
RL   Cancer Res. 47:2903-2910(1987).
//
RX   PubMed=3165706;
RA   Siegfried J.M., Owens S.E.;
RT   "Response of primary human lung carcinomas to autocrine growth factors
RT   produced by a lung carcinoma cell line.";
RL   Cancer Res. 48:4976-4981(1988).
//