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Cellosaurus ECC4 [Human cholangiocarcinoma] (CVCL_A1ZB)

[Text version]
Cell line name ECC4 [Human cholangiocarcinoma]
Synonyms ICC3
Accession CVCL_A1ZB
Resource Identification Initiative To cite this cell line use: ECC4 [Human cholangiocarcinoma] (RRID:CVCL_A1ZB)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Sequence variations
  • Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.Ala615fs (c.1843_1844insC); Zygosity=Homozygous (DepMap=ACH-001843).
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser33Pro (c.97T>C); ClinVar=VCV000376391; Zygosity=Heterozygous (DepMap=ACH-001843).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (DepMap=ACH-001843).
Disease Cholangiocarcinoma (NCIt: C4436)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001843

Markers:
AmelogeninX
CSF1PO9,10
D3S135814,15
D5S81810,12
D7S8207,11
D8S117912,14
D13S31712,14
D16S53911,12
D18S5112
D21S1127,28
FGA20,23
Penta D10,12
Penta E5,12
TH016,9.3
TPOX8
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vijay V., Karisani N., Shi L., Hung Y.-H., Vu P., Kattel P., Kenney L., Merritt J., Adil R., Wu Q.-B., Zhen Y.-L., Morris R., Kreuzer J., Kathiresan M., Herrera Lopez X.I., Ellis H., Gritti I.G., Lecorgne L., Farag I., Popa A., Shen W., Kato H., Xu Q., Balasooriya E.R., Wu M.-J., Chaturantabut S., Kelley R.K., Cleary J.M., Lawrence M.S., Root D.E., Benes C.H., Deshpande V., Juric D., Sellers W.R., Ferrone C.R., Haas W., Vazquez F., Getz G., Bardeesy N.M.
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1ZB
Cell_Model_Passport; SIDM01979
DepMap; ACH-001843
Encyclopedic resources Wikidata; Q105509600
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number7