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Cellosaurus ICC6 (CVCL_A1VF)

[Text version]
Cell line name ICC6
Accession CVCL_A1VF
Resource Identification Initiative To cite this cell line use: ICC6 (RRID:CVCL_A1VF)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Thr (c.395A>C); ClinVar=VCV000376627; Zygosity=Unspecified (DepMap=ACH-001846).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys135Phe (c.404G>T); ClinVar=VCV000376559; Zygosity=Unspecified (DepMap=ACH-001846).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001846

Markers:
AmelogeninX
CSF1PO12,13
D3S135814,15
D5S81811,12
D7S82010
D8S117913
D13S31712
D16S53911,12
D18S5113
D21S1130
FGA20,21
Penta D15
Penta E12,19
TH016,9.3
TPOX8
vWA14,20

Run an STR similarity search on this cell line
Publications

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vijay V., Karisani N., Shi L., Hung Y.-H., Vu P., Kattel P., Kenney L., Merritt J., Adil R., Wu Q.-B., Zhen Y.-L., Morris R., Kreuzer J., Kathiresan M., Herrera Lopez X.I., Ellis H., Gritti I.G., Lecorgne L., Farag I., Popa A., Shen W., Kato H., Xu Q., Balasooriya E.R., Wu M.-J., Chaturantabut S., Kelley R.K., Cleary J.M., Lawrence M.S., Root D.E., Benes C.H., Deshpande V., Juric D., Sellers W.R., Ferrone C.R., Haas W., Vazquez F., Getz G., Bardeesy N.M.
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1VF
DepMap; ACH-001846
Encyclopedic resources Wikidata; Q105509606
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number8