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Cellosaurus AOVC1 (CVCL_A1UI)

[Text version]
Cell line name AOVC1
Synonyms ECC2
Accession CVCL_A1UI
Resource Identification Initiative To cite this cell line use: AOVC1 (RRID:CVCL_A1UI)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Derived from site: In situ; Pancreas, ampulla of Vater; UBERON=UBERON_0004913.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (DepMap=ACH-001997).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln104Ter (c.310C>T); ClinVar=VCV000566924; Zygosity=Unspecified (DepMap=ACH-001997).
Disease Ampulla of Vater adenocarcinoma (NCIt: C6650)
Carcinoma of the ampulla of Vater (ORDO: Orphanet_300557)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001997

Markers:
AmelogeninX,Y
CSF1PO11
D3S135814,16
D5S81810
D7S82010,12
D8S117914,16
D13S31711,12
D16S5399,13
D18S5115,16
D21S1129,31
FGA21
Penta D9,14
Penta E13,16
TH019,9.3
TPOX9
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vijay V., Karisani N., Shi L., Hung Y.-H., Vu P., Kattel P., Kenney L., Merritt J., Adil R., Wu Q.-B., Zhen Y.-L., Morris R., Kreuzer J., Kathiresan M., Herrera Lopez X.I., Ellis H., Gritti I.G., Lecorgne L., Farag I., Popa A., Shen W., Kato H., Xu Q., Balasooriya E.R., Wu M.-J., Chaturantabut S., Kelley R.K., Cleary J.M., Lawrence M.S., Root D.E., Benes C.H., Deshpande V., Juric D., Sellers W.R., Ferrone C.R., Haas W., Vazquez F., Getz G., Bardeesy N.M.
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1UI
Cell_Model_Passport; SIDM01985
DepMap; ACH-001997
Encyclopedic resources Wikidata; Q105506803
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number8