Cellosaurus cell line Hep-11 (CVCL

Cellosaurus Hep-11 (CVCL_A1RR)

Cross-references
Cell line name	Hep-11
Accession	CVCL_A1RR
Resource Identification Initiative	To cite this cell line use: Hep-11 (RRID:CVCL_A1RR)
Comments	Group: Patented cell line. Registration: International Depositary Authority, China General Microbiological Culture Collection Center; CGMCC No.3203. Population: Chinese. Doubling time: 44 hours (PubMed=19929456). Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV). Omics: Array-based CGH. Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249Ser (c.747G>T); ClinVar=VCV000012352; Zygosity=Unspecified (PubMed=19897602).
Disease	Adult hepatocellular carcinoma (NCIt: C7956) Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_A1RS ! Hep-12
Sex of cell	Male
Age at sampling	46Y
Category	Cancer cell line
Publications	PubMed=19897602; DOI=10.1093/carcin/bgp232 Xu X.-L., Xing B.-C., Han H.-B., Zhao W., Hu M.-H., Xu Z.-L., Li J.-Y., Xie Y., Gu J., Wang Y., Zhang Z.-Q. The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor. Carcinogenesis 31:167-174(2010) PubMed=19929456; DOI=10.3109/14653240903390803 Xu X.-L., Xing B.-C., Hu M.-H., Xu Z.-L., Xie Y., Dai G.-H., Gu J., Wang Y., Zhang Z.-Q. Recurrent hepatocellular carcinoma cells with stem cell-like properties: possible targets for immunotherapy. Cytotherapy 12:190-200(2010) Patent=CN101693886B Xing B.-C., Wang X., Xu X.-L., Du X.-J., Ke Y. Liver cancer cell line and application thereof. Patent number CN101693886B, 06-Jun-2012
Cell line databases/resources	cancercelllines; CVCL_A1RR
Encyclopedic resources	Wikidata; Q105507637
Entry history
Entry creation	12-Jan-2021
Last entry update	19-Dec-2024
Version number	7