Cellosaurus logo
expasy logo

Cellosaurus TRA-1-60 (CVCL_A1QS)

[Text version]
Cell line name TRA-1-60
Synonyms Tra-1-60; TRA-1-60 cl.A
Accession CVCL_A1QS
Resource Identification Initiative To cite this cell line use: TRA-1-60 (RRID:CVCL_A1QS)
Comments Biotechnology: The monoclonal antibody produced by this hybridoma along with that produced by TRA-1-81 (Cellosaurus=CVCL_A1QT) are widely used in human stem cell research as positive indicators of a true pluripotent human stem cell.
Monoclonal antibody isotype: IgM.
Monoclonal antibody target: Type 1 lactosamine minimal epitope Galbeta1-3GlcNAcbeta1-3Galbeta1-4GlcNAc (Note=Recognizes human podocalyxin).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

PubMed=6396197; DOI=10.1089/hyb.1984.3.347
Andrews P.W., Banting G.S., Damjanov I., Arnaud D., Avner P.
Three monoclonal antibodies defining distinct differentiation antigens associated with different high molecular weight polypeptides on the surface of human embryonal carcinoma cells.
Hybridoma 3:347-361(1984)

PubMed=21159783; DOI=10.1093/glycob/cwq209; PMCID=PMC3150112
Natunen S., Satomaa T., Pitkanen V., Salo H., Mikkola M., Natunen J., Otonkoski T., Valmu L.
The binding specificity of the marker antibodies Tra-1-60 and Tra-1-81 reveals a novel pluripotency-associated type 1 lactosamine epitope.
Glycobiology 21:1125-1130(2011)

Cross-references
Encyclopedic resources Wikidata; Q105511260
Entry history
Entry creation12-Jan-2021
Last entry update21-Mar-2023
Version number5