Cellosaurus cell line Pan2MmLuc (CVCL

Cellosaurus Pan2MmLuc (CVCL_A1IJ)

Cross-references
Cell line name	Pan2MmLuc
Accession	CVCL_A1IJ
Resource Identification Initiative	To cite this cell line use: Pan2MmLuc (RRID:CVCL_A1IJ)
Comments	Population: Japanese. Characteristics: Metastatic. Established from the orthopical implementation of the TCC-pan2 cell line in BALB/c nu/nu nude mice. Doubling time: ~24 hours (PubMed=30747829). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=30747829). Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=30747829). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Heterozygous (PubMed=30747829). Mutation; HGNC; HGNC:11998; TP53; Simple; c.993+1G>A (IVS9+1G>A); ClinVar=VCV000528261; Zygosity=Homozygous; Note=Splice donor mutation (PubMed=30747829).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_A1II (Pan2M)
Sex of cell	Female
Age at sampling	47Y
Category	Cancer cell line
Publications	PubMed=30747829; DOI=10.1097/MPA.0000000000001253; PMCID=PMC6426353 Yanagihara K., Kubo T., Mihara K., Kuwata T., Ochiai A., Seyama T., Yokozaki H. Development and biological analysis of a novel orthotopic peritoneal dissemination mouse model generated using a pancreatic ductal adenocarcinoma cell line. Pancreas 48:315-322(2019)
Cell line collections (Providers)	JCRB; NIHS1359 - Discontinued
Cell line databases/resources	cancercelllines; CVCL_A1IJ
Encyclopedic resources	Wikidata; Q102114733
Entry history
Entry creation	29-Oct-2020
Last entry update	19-Dec-2024
Version number	9