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Cellosaurus TLBR-2 (CVCL_A1EY)

[Text version]
Cell line name TLBR-2
Synonyms TLBR 2; TLBR2; T-cell Lymphoma BReast-2
Accession CVCL_A1EY
Resource Identification Initiative To cite this cell line use: TLBR-2 (RRID:CVCL_A1EY)
Comments Doubling time: 37 hours (PubMed=22791880); ~24-30 hours (DSMZ=ACC-905).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
Disease Anaplastic large cell lymphoma, ALK-negative (NCIt: C37194)
ALK-negative anaplastic large cell lymphoma (ORDO: Orphanet_300903)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-905

Markers:
AmelogeninX
CSF1PO11,12,13
D2S133816,24
D3S135814,17
D5S81811,13
D7S82011,12
D8S117912,16
D13S3178
D16S53912
D18S5115,16
D19S43312,13
D21S1131,32.2
FGA21
Penta D10,11
Penta E11
TH016
TPOX9,11
vWA14,16

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Publications

PubMed=22791880; DOI=10.1158/1078-0432.CCR-12-0101
Lechner M.G., Megiel C., Church C.H., Angell T.E., Russell S.M., Sevell R.B., Jang J.K., Brody G.S., Epstein A.L.
Survival signals and targets for therapy in breast implant-associated ALK -- anaplastic large cell lymphoma.
Clin. Cancer Res. 18:4549-4559(2012)

PubMed=28356514; DOI=10.1073/pnas.1700682114; PMCID=PMC5393253
Chen J., Zhang Y., Petrus M.N., Xiao W.-M., Nicolae A., Raffeld M., Pittaluga S., Bamford R.N., Nakagawa M., Ouyang S.T.-Y., Epstein A.L., Kadin M.E., Del Mistro A., Woessner R.D., Jaffe E.S., Waldmann T.A.
Cytokine receptor signaling is required for the survival of ALK- anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations.
Proc. Natl. Acad. Sci. U.S.A. 114:3975-3980(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-905
Cell line databases/resources cancercelllines; CVCL_A1EY
DSMZCellDive; ACC-905
Encyclopedic resources Wikidata; Q102114991
Gene expression databases GEO; GSM2527950
Polymorphism and mutation databases Cosmic; 2814461
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number10