Cellosaurus cell line JC-49 (CVCL

Cross-references
Cell line name	JC-49
Synonyms	JFCR-Colorectal-49
Accession	CVCL_A1EQ
Resource Identification Initiative	To cite this cell line use: JC-49 (RRID:CVCL_A1EQ)
Comments	Population: Japanese.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Arg302Ter (c.904C>T) (R284*); ClinVar=VCV000000798; Zygosity=Unspecified (PubMed=28179481). Mutation; HGNC; HGNC:583; APC; Simple; p.Glu1345Ter (c.4033G>T); ClinVar=VCV000449334; Zygosity=Unspecified (PubMed=28179481).
Disease	Colorectal carcinoma (NCIt: C2955)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=28179481; DOI=10.1158/1535-7163.MCT-16-0578 Tanaka N., Mashima T., Mizutani A., Sato A., Aoyama A., Gong B., Yoshida H., Muramatsu Y., Nakata K., Matsuura M., Katayama R., Nagayama S., Fujita N., Sugimoto Y., Seimiya H. APC mutations as a potential biomarker for sensitivity to tankyrase inhibitors in colorectal cancer. Mol. Cancer Ther. 16:752-762(2017)
Cell line databases/resources	cancercelllines; CVCL_A1EQ
Encyclopedic resources	Wikidata; Q102114301
Polymorphism and mutation databases	Cosmic; 2811065
Entry history
Entry creation	29-Oct-2020
Last entry update	19-Dec-2024
Version number	6