Cellosaurus cell line Ma-Mel-62 (CVCL

Cellosaurus Ma-Mel-62 (CVCL_A197)

Cross-references
Cell line name	Ma-Mel-62
Synonyms	MaMel62
Accession	CVCL_A197
Resource Identification Initiative	To cite this cell line use: Ma-Mel-62 (RRID:CVCL_A197)
Comments	Omics: SNP array analysis. Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations	Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease	Cutaneous nodular melanoma (NCIt: C4225)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	17Y
Category	Cancer cell line
Publications	PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595 Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D. B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis. PLoS ONE 2:E236-E236(2007) PubMed=20544847; DOI=10.1002/gcc.20785 Gast A., Scherer D., Chen B.-W., Bloethner S., Melchert S., Sucker A., Hemminki K., Schadendorf D., Kumar R. Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study. Genes Chromosomes Cancer 49:733-745(2010) PubMed=23348503; DOI=10.1126/science.1230062 Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R. TERT promoter mutations in familial and sporadic melanoma. Science 339:959-961(2013)
Cell line databases/resources	cancercelllines; CVCL_A197 IGRhCellID; MaMel62
Encyclopedic resources	Wikidata; Q54903835
Gene expression databases	GEO; GSM437016
Polymorphism and mutation databases	Cosmic; 1467765 Cosmic; 1846655 Cosmic; 2686453 Progenetix; CVCL_A197
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	19