Cellosaurus cell line Ma-Mel-22 (CVCL

Cellosaurus Ma-Mel-22 (CVCL_A159)

[Text version]

Cell line name

Ma-Mel-22

Accession

CVCL_A159

Resource Identification Initiative

To cite this cell line use: Ma-Mel-22 (RRID:CVCL_A159)

Comments

Derived from site: Metastatic; Kidney; UBERON=UBERON_0002113.

Sequence variations

Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

78Y

Category

Cancer cell line

STR profile

Source(s): ECACC=13012452

Markers:

Amelogenin	X
CSF1PO	10,13
D5S818	12
D7S820	10,12
D13S317	8,11
D16S539	11,14
TH01	9.3
TPOX	8,11
vWA	17,18

Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references

Cell line collections (Providers)

ECACC; 13012452

Cell line databases/resources

cancercelllines; CVCL_A159
ESTDAB; ESTDAB-143

Encyclopedic resources

Wikidata; Q54903770

Polymorphism and mutation databases

Cosmic; 1846603
Cosmic; 2686382

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number