Cellosaurus cell line Ma-Mel-14 (CVCL

Cellosaurus Ma-Mel-14 (CVCL_A150)

[Text version]

Cell line name

Ma-Mel-14

Accession

CVCL_A150

Resource Identification Initiative

To cite this cell line use: Ma-Mel-14 (RRID:CVCL_A150)

Comments

Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

64Y

Category

Cancer cell line

STR profile

Source(s): ESTDAB=ESTDAB-210

Markers:

Amelogenin	X
CSF1PO	10
D3S1358	15,16
D5S818	12
D7S820	8,10
D13S317	9
FGA	20,23
TH01	7
TPOX	9,12
vWA	16,17

Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_A150
ESTDAB; ESTDAB-210

Encyclopedic resources

Wikidata; Q54903761

Polymorphism and mutation databases

Cosmic; 1181758
Cosmic; 1846595
Cosmic; 2686371

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number