| Cell line name |
Ma-Mel-134 |
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| Synonyms |
MaMel134 |
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| Accession |
CVCL_A148 |
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| Resource Identification Initiative |
To cite this cell line use: Ma-Mel-134 (RRID:CVCL_A148) |
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| Comments |
Omics: SNP array analysis. |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Heterozygous (PubMed=20544847).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23348503).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Leu108Pro (c.323T>C); ClinVar=VCV000418436; Zygosity=Unspecified (PubMed=20544847).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.242_243CC>TT (-138/-139CC>TT); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
|
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| Disease |
Melanoma (NCIt: C3224) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Category |
Cancer cell line |
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| Publications | PubMed=20544847; DOI=10.1002/gcc.20785
Gast A., Scherer D., Chen B.-W., Bloethner S., Melchert S., Sucker A., Hemminki K., Schadendorf D., Kumar R.
Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study.
Genes Chromosomes Cancer 49:733-745(2010) PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_A148
IGRhCellID; MaMel134
|
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| Encyclopedic resources |
Wikidata; Q54903759
|
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| Gene expression databases |
GEO; GSM437043
|
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| Polymorphism and mutation databases |
Cosmic; 1467792
Cosmic; 1846593
Cosmic; 2686369
Progenetix; CVCL_A148
|
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| Entry history |
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| Entry creation | 06-Jun-2012 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 16 |
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