Cellosaurus cell line Ma-Mel-126 (CVCL

Cellosaurus Ma-Mel-126 (CVCL_A144)

Cross-references
Cell line name	Ma-Mel-126
Synonyms	MaMel126
Accession	CVCL_A144
Resource Identification Initiative	To cite this cell line use: Ma-Mel-126 (RRID:CVCL_A144)
Comments	Omics: SNP array analysis.
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=23348503). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly266Val (c.797G>T); ClinVar=VCV000233303; Zygosity=Unspecified (PubMed=20544847).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=20544847; DOI=10.1002/gcc.20785 Gast A., Scherer D., Chen B.-W., Bloethner S., Melchert S., Sucker A., Hemminki K., Schadendorf D., Kumar R. Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study. Genes Chromosomes Cancer 49:733-745(2010) PubMed=23348503; DOI=10.1126/science.1230062 Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R. TERT promoter mutations in familial and sporadic melanoma. Science 339:959-961(2013)
Cell line databases/resources	cancercelllines; CVCL_A144 IGRhCellID; MaMel126
Encyclopedic resources	Wikidata; Q54903755
Gene expression databases	GEO; GSM437039
Polymorphism and mutation databases	Cosmic; 1467789 Cosmic; 1846589 Cosmic; 2686364 Progenetix; CVCL_A144
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	16