Cellosaurus cell line Ma-Mel-12 (CVCL

Cellosaurus Ma-Mel-12 (CVCL_A139)

Cross-references
Cell line name	Ma-Mel-12
Synonyms	Ma-Mel_12; Ma-Mel 12; MaMel12
Accession	CVCL_A139
Resource Identification Initiative	To cite this cell line use: Ma-Mel-12 (RRID:CVCL_A139)
Comments	Omics: SNP array analysis. Omics: Transcriptome analysis by microarray.
Sequence variations	Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R. Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature. Pigment Cell Res. 19:290-302(2006) PubMed=20544847; DOI=10.1002/gcc.20785 Gast A., Scherer D., Chen B.-W., Bloethner S., Melchert S., Sucker A., Hemminki K., Schadendorf D., Kumar R. Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study. Genes Chromosomes Cancer 49:733-745(2010) PubMed=23348503; DOI=10.1126/science.1230062 Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R. TERT promoter mutations in familial and sporadic melanoma. Science 339:959-961(2013)
Cell line databases/resources	cancercelllines; CVCL_A139 ESTDAB; ESTDAB-103
Anatomy/cell type resources	BTO; BTO_0005340
Encyclopedic resources	Wikidata; Q54903750
Gene expression databases	GEO; GSM109054 GEO; GSM436992
Polymorphism and mutation databases	Cosmic; 1467741 Cosmic; 1846584 Cosmic; 2686357 Progenetix; CVCL_A139
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	14