| Cell line name |
Ma-Mel-105 |
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| Accession |
CVCL_A130 |
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| Resource Identification Initiative |
To cite this cell line use: Ma-Mel-105 (RRID:CVCL_A130) |
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| Comments |
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107. |
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| Sequence variations |
- Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-126C>T (c.230C>T) (C230T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
|
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| Disease |
Melanoma (NCIt: C3224) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
48Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007) PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_A130
|
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| Encyclopedic resources |
Wikidata; Q54903741
|
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| Polymorphism and mutation databases |
Cosmic; 1846575
Cosmic; 2686345
|
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| Entry history |
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| Entry creation | 06-Jun-2012 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 18 |
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