ID   SHG-140
AC   CVCL_A0XC
SY   SHG140; Suzhou Human Glioma-140
DR   cancercelllines; CVCL_A0XC
DR   Wikidata; Q108821302
RX   PubMed=33391433;
CC   Population: Chinese.
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Val178Ile (c.532G>A); ClinVar=VCV000134520; Zygosity=Homozygous (PubMed=33391433).
CC   Sequence variation: Mutation; HGNC; HGNC:7765; NF1; Simple; p.Arg1968Ter (c.5902C>T) (p.Arg1947Ter, c.5839C>T); ClinVar=VCV000000343; Zygosity=Homozygous (PubMed=33391433).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Homozygous (PubMed=33391433).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (PubMed=33391433).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
ST   Source(s): PubMed=33391433
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D12S391: 17,20
ST   D13S317: 9
ST   D16S539: 11
ST   D18S51: 21
ST   D19S433: 13,14
ST   D21S11: 29,30
ST   D2S1338: 24
ST   D3S1358: 15,17
ST   D5S818: 12
ST   D6S1043: 19
ST   D7S820: 10,12
ST   D8S1179: 12,15
ST   FGA: 24,25
ST   Penta D: 9,13
ST   Penta E: 16
ST   TH01: 9
ST   TPOX: 8
ST   vWA: 16,17
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 19-12-24; Version: 6
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RX   PubMed=33391433; DOI=10.7150/jca.40802; PMCID=PMC7738992;
RA   Li Y.-Y., Sun T., Chen Z., Shao Y.-X., Huang Y.-L., Zhou Y.-X.;
RT   "Characterization of a new human astrocytoma cell line SHG140: cell
RT   proliferation, cell phenotype, karyotype, STR markers and
RT   tumorigenicity analysis.";
RL   J. Cancer 12:371-378(2021).
//