Cellosaurus cell line SRH (CVCL

Cellosaurus SRH (CVCL_A0XB)

[Text version]

Cell line name

SRH

Accession

CVCL_A0XB

Resource Identification Initiative

To cite this cell line use: SRH (RRID:CVCL_A0XB)

Comments

Doubling time: 34.3 +- 2.5 hours (PubMed=33322555).
Omics: Array-based CGH.
Derived from site: In situ; Left leg, skeletal muscle; UBERON=UBERON_0001383.

Sequence variations

Mutation; HGNC; HGNC:7611; MYOD1; Simple; p.Leu122Arg (c.365T>G); Zygosity=Homozygous (PubMed=33322555).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (PubMed=33322555).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Unspecified (PubMed=33322555).

Disease

Spindle cell/sclerosing rhabdomyosarcoma (NCIt: C121654)
Rhabdomyosarcoma (ORDO: Orphanet_780)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

24Y

Category

Cancer cell line

STR profile

Source(s): PubMed=33322555

Markers:

Amelogenin	X
CSF1PO	11,12
D5S818	12
D7S820	8,11
D13S317	11
D16S539	11,12
D21S11	29,31.2
TH01	9.3
TPOX	8,9
vWA	14,17

Publications

PubMed=33322555; DOI=10.3390/cells9122668; PMCID=PMC7763666
Schleicher S., Grote S., Malenke E., Chan K.C.-H., Schaller M., Fehrenbacher B., Riester R., Kluba T., Frauenfeld L., Boesmueller H., Gohring G., Schlegelberger B., Handgretinger R., Kopp H.-G., Traub F., Boehme K.A.
Establishment and characterization of a sclerosing spindle cell rhabdomyosarcoma cell line with a complex genomic profile.
Cells 9:2668.1-2668.26(2020)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_A0XB

Encyclopedic resources

Wikidata; Q108821326

Entry history

Entry creation

23-Sep-2021

Last entry update

19-Dec-2024

Version number