ID   mes-c-myc A1
AC   CVCL_A0WM
SY   A1 mes c-myc; A1
DR   Wikidata; Q108820901
RX   PubMed=10527628;
RX   PubMed=23246712;
RX   PubMed=33498778;
CC   Characteristics: Cease to divide and undergo morphological differentiation after serum withdrawal or addition of cAMP (PubMed=10527628).
CC   Characteristics: Established by infection with a replication-defective retrovirus bearing the MYC and neo genes under the control of MLV LTR promoter.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7553; MYC.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: Myc.
CC   Omics: Secretome proteome analysis.
CC   Derived from site: In situ; Embryonic brain, mesencephalon; UBERON=UBERON_0009616.
CC   Breed/subspecies: CD-1.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   11FD
CA   Transformed cell line
DT   Created: 23-09-21; Last updated: 19-12-24; Version: 8
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RX   PubMed=10527628; DOI=10.1006/excr.1999.4636;
RA   Colucci-D'Amato G.L., Tino A., Pernas-Alonso R., ffrench-Mullen J.M.H.,
RA   di Porzio U.;
RT   "Neuronal and glial properties coexist in a novel mouse CNS
RT   immortalized cell line.";
RL   Exp. Cell Res. 252:383-391(1999).
//
RX   PubMed=23246712; DOI=10.1016/j.bbapap.2012.12.005;
RA   Severino V., Farina A., Colucci-D'Amato G.L., Reccia M.G.,
RA   Volpicelli F., Parente A., Chambery A.;
RT   "Secretome profiling of differentiated neural mes-c-myc A1 cell line
RT   endowed with stem cell properties.";
RL   Biochim. Biophys. Acta 1834:2385-2395(2013).
//
RX   PubMed=33498778; DOI=10.3390/ijms22031124; PMCID=PMC7865411;
RA   Reccia M.G., Volpicelli F., Benedikz E., Svenningsen A.F.,
RA   Colucci-D'Amato G.L.;
RT   "Generation of high-yield, functional oligodendrocytes from a c-myc
RT   immortalized neural cell line, endowed with staminal properties.";
RL   Int. J. Mol. Sci. 22:1124.1-1124.18(2021).
//