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Cellosaurus MS-EwS-34 (CVCL_A0VR)

[Text version]
Cell line name MS-EwS-34
Accession CVCL_A0VR
Resource Identification Initiative To cite this cell line use: MS-EwS-34 (RRID:CVCL_A0VR)
Comments Miscellaneous: Gene fusion, site of sampling, sex and age of donor from personal communication of Rossig, Claudia.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:3446; ERG + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ERG, EWS-ERG (Direct_author_submission).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
STR profile Source(s): PubMed=30879952

Markers:
AmelogeninX
CSF1PO12
D3S135815,18
D5S81811
D7S82010,12
D13S3179,11
D16S53912
FGA19,23
TH016,8
TPOX8,10
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=30879952; DOI=10.1016/j.ymthe.2019.02.014; PMCID=PMC6520468
Kailayangiri S., Altvater B., Lesch S., Balbach S.T., Gottlich C., Kuhnemundt J., Mikesch J.-H., Schelhaas S., Jamitzky S., Meltzer J., Farwick N., Greune L., Fluegge M., Kerl K., Lode H.N., Siebert N., Muller I., Walles H., Hartmann W., Rossig C.
EZH2 inhibition in Ewing sarcoma upregulates GD2 expression for targeting with gene-modified T cells.
Mol. Ther. 27:933-946(2019)

Cross-references
Encyclopedic resources Wikidata; Q108820991
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number6