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Cellosaurus MS-EwS-15 (CVCL_A0VP)

[Text version]
Cell line name MS-EwS-15
Synonyms DC-ES-15
Accession CVCL_A0VP
Resource Identification Initiative To cite this cell line use: MS-EwS-15 (RRID:CVCL_A0VP)
Comments Miscellaneous: Gene fusion from personal communication of Rossig, Claudia.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (Direct_author_submission).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=30879952

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135815,17
D5S81811
D7S8208,11
D13S31714
D16S53912,13
FGA20,22
TH016
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=30879952; DOI=10.1016/j.ymthe.2019.02.014; PMCID=PMC6520468
Kailayangiri S., Altvater B., Lesch S., Balbach S.T., Gottlich C., Kuhnemundt J., Mikesch J.-H., Schelhaas S., Jamitzky S., Meltzer J., Farwick N., Greune L., Fluegge M., Kerl K., Lode H.N., Siebert N., Muller I., Walles H., Hartmann W., Rossig C.
EZH2 inhibition in Ewing sarcoma upregulates GD2 expression for targeting with gene-modified T cells.
Mol. Ther. 27:933-946(2019)

Cross-references
Encyclopedic resources Wikidata; Q108820987
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number6