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Cellosaurus CDina26 (CVCL_A0IM)

[Text version]
Cell line name CDina26
Synonyms BT 5/9; BT5/9; 5/9
Accession CVCL_A0IM
Resource Identification Initiative To cite this cell line use: CDina26 (RRID:CVCL_A0IM)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Advanced Biotechnology Center (ABC), Interlab Cell Line Collection (ICLC), Italy; PD 12002.
Biotechnology: Was used to produce the monoclonal antibody begelomab (Begedina) which was evaluated as a therapeutic agent against steroid-resistant acute graft-versus-host disease.
Monoclonal antibody isotype: IgG2b.
Monoclonal antibody target: UniProtKB; P27487; Human DPP4/CD26.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_3412 (P3X63Ag8U.1)
Category Hybridoma
Publications

PubMed=6459366; DOI=10.4049/jimmunol.128.1.16
Corte G., Mingari M.C., Moretta A., Damiani G., Moretta L., Bargellesi A.
Human T cell subpopulations defined by a monoclonal antibody. I. A small subset is responsible for proliferation to allogeneic cells or to soluble antigens and for helper activity for B cell differentiation.
J. Immunol. 128:16-19(1982)

Patent=US9376498
Di Naro A.F.
Anti-CD26 antibodies and uses thereof.
Patent number US9376498, 28-Jun-2016

Patent=US10208126
Di Naro A.F.
Methods of treating aplastic anemia by administering anti-CD26 antibodies.
Patent number US10208126, 19-Feb-2019

Cross-references
Biological sample resources ABCD; ABCD_AA723
Encyclopedic resources Wikidata; Q108820000
Entry history
Entry creation23-Sep-2021
Last entry update21-Mar-2023
Version number3