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Cellosaurus LAPC4-CR (CVCL_A0BW)

[Text version]
Cell line name LAPC4-CR
Accession CVCL_A0BW
Resource Identification Initiative To cite this cell line use: LAPC4-CR (RRID:CVCL_A0BW)
Comments Characteristics: Derived after 4 passages of the parent cell line in castrated nude mice.
Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (from parent cell line).
Doubling time: ~50 hours (PubMed=34402095).
Omics: Deep proteome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4744 (LAPC-4)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=34402095; DOI=10.1002/pros.24210; PMCID=PMC8460612
Haffner M.C., Bhamidipati A., Tsai H.K., Esopi D.M., Vaghasia A.M., Low J.-Y., Patel R.A., Guner G., Pham M.-T., Castagna N., Hicks J.L., Wyhs N., Aebersold R., De Marzo A.M., Nelson W.G., Guo T.-N., Yegnasubramanian S.
Phenotypic characterization of two novel cell line models of castration-resistant prostate cancer.
Prostate 81:1159-1171(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A0BW
Encyclopedic resources Wikidata; Q108820668
Gene expression databases GEO; GSM5402199
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number9