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Cellosaurus YCUB-6 (CVCL_A087)

[Text version]
Cell line name YCUB-6
Synonyms YCUB6; YcuB6; Yokohama City University BCP-ALL-6
Accession CVCL_A087
Resource Identification Initiative To cite this cell line use: YCUB-6 (RRID:CVCL_A087)
Comments Population: Japanese.
Doubling time: ~3-4 days (DSMZ=ACC-966).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease B acute lymphoblastic leukemia with t(1;19)(q23;p13.3) E2A-PBX1 (TCF3-PBX1) (NCIt: C80347)
B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) (ORDO: Orphanet_585956)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 12Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-966

Markers:
AmelogeninX,Y
CSF1PO10,13
D2S133820,24
D3S135812,17
D5S81813,14
D7S82011
D8S117914
D13S3178,9
D16S5399,10
D18S5114,16
D19S43314,16
D21S1129,32.2
FGA22,24
Penta D12,13
Penta E8,10
TH017,9
TPOX8,9
vWA16,19

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Publications

PubMed=19157546; DOI=10.1016/j.leukres.2008.12.003
Goto H., Naruto T., Tanoshima R., Kato H., Yokosuka T., Yanagimachi M., Fujii H., Yokota S., Komine H.
Chemo-sensitivity in a panel of B-cell precursor acute lymphoblastic leukemia cell lines, YCUB series, derived from children.
Leuk. Res. 33:1386-1391(2009)

PubMed=29786757; DOI=10.1007/s12185-018-2474-7
Tomoyasu C., Imamura T., Tomii T., Yano M., Asai D., Goto H., Shimada A., Sanada M., Iwamoto S., Takita J., Minegishi M., Inukai T., Sugita K., Hosoi H.
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.
Int. J. Hematol. 108:312-318(2018)

PubMed=32144432; DOI=10.1007/s00280-020-04045-9
Goto H., Yoshino Y., Ito M., Nagai J.-i., Kumamoto T., Inukai T., Sakurai Y., Miyagawa N., Keino D., Yokosuka T., Iwasaki F., Hamanoue S., Shiomi M., Goto S.
Aurora B kinase as a therapeutic target in acute lymphoblastic leukemia.
Cancer Chemother. Pharmacol. 85:773-783(2020)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

Cross-references
Cell line collections (Providers) DSMZ; ACC-966
Encyclopedic resources Wikidata; Q54995379
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number13