ID   YCUB-4R
AC   CVCL_A084
SY   YCUB4R; Yokohama City University BCP-ALL-4 Relapse
DR   ArrayExpress; E-MTAB-11038
DR   ArrayExpress; E-MTAB-11039
DR   DSMZ; ACC-963
DR   Wikidata; Q54995374
RX   PubMed=19157546;
RX   PubMed=34940123;
CC   Population: Japanese.
CC   Doubling time: ~48 hours (DSMZ=ACC-963).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=34940123).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (PubMed=34940123).
CC   Sequence variation: Gene fusion; HGNC; HGNC:1008; BCL9 + HGNC; HGNC:6997; MEF2D; Name(s)=MEF2D-BCL9; Note=MEF2D exon5/BCL9 exon 9 fusion (PubMed=34940123).
CC   Omics: Array-based CGH.
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): DSMZ=ACC-963
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 8
ST   D16S539: 9
ST   D18S51: 17,18
ST   D19S433: 13,14
ST   D21S11: 31,33.2
ST   D2S1338: 17,22
ST   D3S1358: 15,17
ST   D5S818: 12,13
ST   D7S820: 10,11
ST   D8S1179: 16
ST   FGA: 25,26
ST   Penta D: 10,11
ST   Penta E: 17,21
ST   TH01: 7
ST   TPOX: 8
ST   vWA: 14,16
DI   NCIt; C9140; Childhood B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A083 ! YCUB-4
SX   Male
AG   7Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 14
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RX   PubMed=19157546; DOI=10.1016/j.leukres.2008.12.003;
RA   Goto H., Naruto T., Tanoshima R., Kato H., Yokosuka T.,
RA   Yanagimachi M., Fujii H., Yokota S., Komine H.;
RT   "Chemo-sensitivity in a panel of B-cell precursor acute lymphoblastic
RT   leukemia cell lines, YCUB series, derived from children.";
RL   Leuk. Res. 33:1386-1391(2009).
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RX   PubMed=34940123; DOI=10.3390/cimb43030149; PMCID=PMC8929001;
RA   Quentmeier H., Pommerenke C., Drexler H.G.;
RT   "Molecular genetics of pre-B acute lymphoblastic leukemia sister cell
RT   lines during disease progression.";
RL   Curr. Issues Mol. Biol. 43:2147-2156(2021).
//